Reduced Susceptibility to Sugar-Induced Metabolic Derangements and Impairments of Myocardial Redox Signaling in Mice Chronically Fed with D-Tagatose when Compared to Fructose
Effects of liquid sugars feeding on myocardial accumulation of AGE and expression of RAGE. Representative Western blotting and relative densitometric analysis of CEL- and CML-glycated proteins (a and b, respectively) and RAGE expression (c) in the heart of mice fed for 24 weeks with a control diet or with a diet containing liquid supplementation of fructose/D-tagatose. Protein expression was measured as relative optical density (OD), corrected for the corresponding tubulin contents and normalized using the related CD band. Values are represented as means ± S.E.M. of 6 animals per group. denotes vs. CD. # denotes vs. L-Tg diet.
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