Research Article

Early Postweaning Treatment with Dimethyl Fumarate Prevents Prenatal Dexamethasone- and Postnatal High-Fat Diet-Induced Programmed Hypertension in Male Rat Offspring

Table 2

Weights and blood pressures.

ControlDEXHFDEX + HFDEX + HF + DMF

Mortality0%0%0%0%0%
Body weight (BW) (g)529 ± 9516 ± 12523 ± 11522 ± 11537 ± 16
Left kidney weight (g)1.7 ± 0.051.77 ± 0.041.63 ± 0.061.58 ± 0.051.69 ± 0.09
Left kidney weight/100 g BW0.32 ± 0.010.34 ± 0.010.31 ± 0.010.3 ± 0.010.31 ± 0.01
Liver weight (g)16.1 ± 0.616.8 ± 0.517.7 ± 0.718.3 ± 0.816.2 ± 1.0
Liver weight/100 g BW3.04 ± 0.063.25 ± 0.053.39 ± 0.173.53 ± 0.193.04 ± 0.2
Systolic blood pressure (mmHg)147 ± 3158 ± 2160 ± 3172 ± 1152 ± 2

versus control; versus DEX; versus HF; versus DEX + HF.