Modulation of Oxidative Status by Normoxia and Hypoxia on Cultures of Human Dermal Fibroblasts: How Does It Affect Cell Aging?

<div>Gene expression analysis of superoxide dismutases (SOD) 1 and 3 and catalase (CAT), in HDF assessed by qPCR. The histograms show the modulation of SOD1 (a), SOD3 (b), and CAT (c) mRNA by oxygen tension (21% O<sub>2</sub> vs 5% O<sub>2</sub>) at matched cell passages in young (Y) and old (O) HDF. The genes were normalized vs GAPDH/<i>β</i>-actin/SDHA and the results are reported as normalized fold expression. 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Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: Modulation of Oxidative Status by Normoxia and Hypoxia on Cultures of Human Dermal Fibroblasts: How Does It Affect Cell Aging? 