Intravitreal Injection of Hydrogen Peroxide Induces Acute Retinal Degeneration, Apoptosis, and Oxidative Stress in Mice

<div>Retinal gene expression analysis after the H2O2 treatment. (a) The schematic diagram of gene expression analysis after the H2O2 treatment. The expression of photoreceptor markers including (b) Rho, (c) Rcvrn, (d) Rora, and (e) Rorb genes was decreased significantly with the increasing dose of H2O2. (f) The expression of Chat gene was decreased significantly after treatment with H2O2. (g) The expression of Calb2 gene was decreased significantly after treatment with 8 μg H2O2. (h) The expression of Tuj1 gene was significantly increased in 10 μg H2O2 group. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Intravitreal Injection of Hydrogen Peroxide Induces Acute Retinal Degeneration, Apoptosis, and Oxidative Stress in Mice 