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Oxidative Medicine and Cellular Longevity
Volume 2018 (2018), Article ID 5763256, 9 pages
https://doi.org/10.1155/2018/5763256
Research Article

Photobiomodulation Leads to Reduced Oxidative Stress in Rats Submitted to High-Intensity Resistive Exercise

1Biophotonic Department, Universidade Nove de Julho, São Paulo, SP, Brazil
2Cardiology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil
3Postgraduate Program of Physical Education, Universidade Federal de Mato Grosso (UFMT), Cuiabá, MT, Brazil
4Postgraduate Program in Nutrition, Food and Metabolism, Universidade Federal de Mato Grosso (UFMT), Cuiabá, MT, Brazil
5Laboratory of Translational Physiology, Universidade Nove de Julho, São Paulo, SP, Brazil
6Centro de Educação Física e Desporto, Universidade Federal do Espírito Santo (UFES), Vitória, ES, Brazil

Correspondence should be addressed to Andrey Jorge Serra

Received 4 August 2017; Revised 11 November 2017; Accepted 29 November 2017; Published 13 February 2018

Academic Editor: Swaran J. S. Flora

Copyright © 2018 Helenita Antonia de Oliveira et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of this study was to determine whether oxidative stress markers are influenced by low-intensity laser therapy (LLLT) in rats subjected to a high-intensity resistive exercise session (RE). Female Wistar rats divided into three experimental groups (Ctr: control, 4J: LLLT, and RE) and subdivided based on the sampling times (instantly or 24 h postexercise) underwent irradiation with LLLT using three-point transcutaneous method on the hind legs, which was applied to the gastrocnemius muscle at the distal, medial, and proximal points. Laser (4J) or placebo (device off) were carried out 60 sec prior to RE that consisted of four climbs bearing the maximum load with a 2 min time interval between each climb. Lipoperoxidation levels and antioxidant capacity were obtained in muscle. Lipoperoxidation levels were increased (4-HNE and CL markers) instantly post-RE. LLLT prior to RE avoided the increase of the lipid peroxidation levels. Similar results were also notified for oxidation protein assays. The GPx and FRAP activities did not reduce instantly or 24 h after RE. SOD increased 24 h after RE, while CAT activity did not change with RE or LLLT. In conclusion, LLLT prior to RE reduced the oxidative stress markers, as well as, avoided reduction, and still increased the antioxidant capacity.