Research Article
Novel Curcumin C66 That Protects Diabetes-Induced Aortic Damage Was Associated with Suppressing JNK2 and Upregulating Nrf2 Expression and Function
Figure 3
Protective effect of C66 or JNK2 deletion on diabetes-induced aortic apoptosis. The apoptotic cell was examined by TUNEL staining (a, b); the expression of caspase-3 mRNA (c) reflects the apoptotic level. ; DM vs. corresponding control group; & DM + C66 vs. corresponding DM; # JNK2−/− mice vs. corresponding WT mice. DM: diabetes mellitus.
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