The Impact of Moderate Chronic Hypoxia and Hyperoxia on the Level of Apoptotic and Autophagic Proteins in Myocardial Tissue

Table 1

Effects of moderate, chronic hypoxia, and hyperoxia on different variables.

	Hypoxia	Hyperoxia
Body weight	↓	↑
Blood hemoglobin	↑	↓
D-ROMs	↑	↔
NOX4	↑	↔
HIF-1α	↑	↔
HIF-2α	↔	↔
Bax/Bcl2	↔	↑
DNA fragmentation	↑	↑
p-Akt	↔	↔
p-AMPK	↔	↔
Beclin-1	↑	↔
LC3B-II	↔	↔
p62	↔	↔