Gossypol from Cottonseeds Ameliorates Glucose Uptake by Mimicking Insulin Signaling and Improves Glucose Homeostasis in Mice with Streptozotocin-Induced Diabetes

<div>Improvement of glucose uptake via the activation of IRS-1 and its downstream signaling pathways in C2C12 myotubes by gossypol (GSP). (a) mRNA expression was analyzed by RT-PCR. (b) Total cell lysates were extracted and subjected to Western blot analysis with the designated antibodies. (c) The immunoblotting signals were quantified using densitometer. 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Rosi: rosiglitazone.</div>

Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Gossypol from Cottonseeds Ameliorates Glucose Uptake by Mimicking Insulin Signaling and Improves Glucose Homeostasis in Mice with Streptozotocin-Induced Diabetes 

Figure 5 | Gossypol from Cottonseeds Ameliorates Glucose Uptake by Mimicking Insulin Signaling and Improves Glucose Homeostasis in Mice with Streptozotocin-Induced Diabetes 