Oxidative Medicine and Cellular Longevity

Research Article

Gossypol from Cottonseeds Ameliorates Glucose Uptake by Mimicking Insulin Signaling and Improves Glucose Homeostasis in Mice with Streptozotocin-Induced Diabetes

Table 1

Kinetic parameters of α-glucosidase in the presence of gossypol (GSP).
CompoundConcentration (mM)Km (mM) ( per min)Mode of inhibition
None—2.26 × 10−414.26 × 10−3 
GSP1 × 10−33.04 × 10−414.11 × 10−3Competitive
2 × 10−34.15 × 10−414.26 × 10−3
3 × 10−36.00 × 10−414.31 × 10−3
4 × 10−39.28 × 10−414.29 × 10−3