Research Article
Age-Dependent Protective Effect of Selenium against UVA Irradiation in Primary Human Keratinocytes and the Associated DNA Repair Signature
Figure 2
Impact of aging on DNA BER capacities of keratinocytes. Using the ODN biochip, cellular extracts of young or old keratinocytes were tested for their excision activities for (a) Tg-A, THF-A, U-G, U-A, and EthA-T and (b) 8oxoG-C and A-8oxoG. Values representing the excision capacity are expressed as the mean percentage of cleavage of total fluorescence intensity ± SD with respect to the initial fluorescence intensity ( donors, 3 independent measurements for each age group). Significantly different (), , and .
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