Antiskin Inflammatory Activity of Black Ginger (Kaempferia parviflora) through Antioxidative Activity

Figure 3

Transcriptional regulation of Kaempferia parviflora extract (KPE) on sUV-induced COX-2 expression. The promoter and transcriptional activity of cox-2 (a) and NF-κB (b) were downregulated by KPE, respectively. The detailed procedure is indicated in Materials and Methods. Briefly, KPE was pretreated to the cells prior to sUV (23 kJ/cm²) irradiation. After 3 h of sUV exposure, each luciferase activity was measured. The pound signs (##) and asterisks () indicate significant difference (of ) compared to the untreated group and sUV-treated group, respectively. (c) The phosphorylation level of c-Jun was detected using Western blot assay with a specific primary antibody. Data are representative of 3 independent experiments that gave similar results.

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