The Effects of Ibogaine on Uterine Smooth Muscle Contractions: Relation to the Activity of Antioxidant Enzymes

Figure 1

The effects of increasing concentrations of ibogaine on uterine contractions. (a) Representative original trace of spontaneously active uterus treated with increasing concentrations of ibogaine (1–40 mg/l); W = washing out. (b) Representative original trace of Ca²⁺-stimulated uterus treated with increasing concentrations of ibogaine (1–60 mg/l). (c) Force of contractions of spontaneously active and Ca²⁺-stimulated active uteri during the control period, before the addition of ibogaine, calculated as area under the curve per minute. Values are means ± SEM () and presented as percentage of Ca²⁺-stimulated contractions. Difference was tested by the t-test. .

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