The Effects of Ibogaine on Uterine Smooth Muscle Contractions: Relation to the Activity of Antioxidant Enzymes

Figure 2

Concentration-response sigmoid fit curves for ibogaine-treated uteri: (a) force of contractions, (b) amplitude, and (c) frequency. Force of contractions, amplitudes, and frequencies were calculated as percentage of controls and expressed as mean values ± SEM (). Differences were tested by two-way ANOVA (factors: type of contraction and concentration of ibogaine). The sigmoid fits were performed according to the Boltzmann equation (fits were compared by the F-test) and EC₅₀ values were expressed. Differences between EC₅₀ values were tested by the t-test. , .

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