Combined Therapy with Extracorporeal Shock Wave and Adipose-Derived Mesenchymal Stem Cells Remarkably Improved Acute Ischemia-Reperfusion Injury of Quadriceps Muscle

Figure 1

Circulating myoglobin and CPK at 12 h and mechanical paw withdrawal threshold (MPWT) at day 7 after the IR procedure. (a) Circulating level of myoglobin. versus other groups with different symbols (†, ‡, §, and ¶), . (b) Circulating level of creatine phosphokinase (CPK). versus other groups with different symbols (†, ‡, §, and ¶), . (c) The value of mechanical paw withdrawal threshold. versus other groups with different symbols (†, ‡, §, and ¶), . All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test ( for each group). Symbols (, †, ‡, §, and ¶) indicate significance at the 0.05 level. SC = sham control; IR = ischemia-reperfusion; ECSW = extracorporeal shock wave; ADMSC = adipose-derived mesenchymal stem cell.

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