Combined Therapy with Extracorporeal Shock Wave and Adipose-Derived Mesenchymal Stem Cells Remarkably Improved Acute Ischemia-Reperfusion Injury of Quadriceps Muscle

Figure 10

Protein expressions of oxidative-stress, apoptotic, antiapoptotic, fibrotic, and antifibrotic biomarkers in the quadriceps by day 7 after the IR procedure. (a) Protein expression of NOX-1. versus other groups with different symbols (†, ‡, §, and ¶), . (b) Protein expression of NOX-2. versus other groups with different symbols (†, ‡, §, and ¶), . (c) Protein expression of cleaved caspase (c-Csp)3. versus other groups with different symbols (†, ‡, §, and ¶), . (d) Protein expression of cleaved poly (ADP-ribose) polymerase (c-PARP). versus other groups with different symbols (†, ‡, §, and ¶), . (e) Protein expression of transforming growth factor- (TGF-) β. versus other groups with different symbols (†, ‡, §, and ¶), . (f) Protein expression of phosphorylated- (p-) Smad3. versus other groups with different symbols (†, ‡, §, and ¶), . (g) Protein expression of Bcl-2. versus other groups with different symbols (†, ‡, §, and ¶), . (h) Protein expression of p-Smad1/5. versus other groups with different symbols (†, ‡, §, and ¶), . (i) Protein expression of bone morphogenetic protein- (BMP-) 2. versus other groups with different symbols (†, ‡, §, and ¶), .

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