Circulating Heme Oxygenase-1: Not a Predictor of Preeclampsia but Highly Expressed in Pregnant Women Who Subsequently Develop Severe Preeclampsia

Figure 2

Plasma (a) and urine (b) HO-1 concentration from pregnant healthy during gestation (control, ) and women who subsequently developed severe () and mild () preeclampsia. Significant differences were found in plasma HO-1 between mild and severe preeclampsia (medians [25th–75th centiles]: 1.38 ng/mL [1.16–2.26] vs. 3.62 ng/mL [1.68–8.16], ). Urine levels were similar among groups (0.33 ± 0.05, 0.32 ± 0.04, and 0.34 ± 0.6, respectively, severe, mild, and control). Boxplot indicates median [min−max]. Comparison of concentration among groups was by Kruskal-Wallis followed by Dunn’s or ANOVA 1-way followed by Tukey’s multiple comparisons test.

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