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Oxidative Medicine and Cellular Longevity
Volume 2018, Article ID 6040149, 11 pages
https://doi.org/10.1155/2018/6040149
Research Article

Identification of Estrogen Receptor α Antagonists from Natural Products via In Vitro and In Silico Approaches

1Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Xian Nong Tan Street, Beijing 100050, China
2Beijing Key Laboratory of Drug Target Research and Drug Screening, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
3State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China

Correspondence should be addressed to Ai-Lin Liu; nc.ca.mmi@niliauil and Guan-Hua Du; nc.ca.mmi@hgud

Xiaocong Pang and Weiqi Fu contributed equally to this work.

Received 15 February 2018; Revised 1 April 2018; Accepted 11 April 2018; Published 10 May 2018

Academic Editor: Valentina Pallottini

Copyright © 2018 Xiaocong Pang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [3 citations]

The following is the list of published articles that have cited the current article.

  • Li-Hua Mu, Hong Yan, Yu-Ning Wang, Teng-Fei Yu, and Ping Liu, “Triterpenoid saponins from Ardisia gigantifolia stapf. and mechanism on inhibiting proliferation of MDA-MB-231 cells,” Biological and Pharmaceutical Bulletin, 2018. View at Publisher · View at Google Scholar
  • J.V. Cotterill, L. Palazzolo, C. Ridgway, N. Price, E. Rorije, A. Moretto, A. Peijnenburg, and I. Eberini, “Predicting estrogen receptor binding of chemicals using a suite of in silico methods – Complementary approaches of (Q)SAR, molecular docking and molecular dynamics,” Toxicology and Applied Pharmacology, pp. 114630, 2019. View at Publisher · View at Google Scholar
  • Hee-Sung Chae, Rong Xu, Jae-Yeon Won, Young-Won Chin, and Hyungshin Yim, “Molecular Targets of Genistein and Its Related Flavonoids to Exert Anticancer Effects,” International Journal of Molecular Sciences, vol. 20, no. 10, pp. 2420, 2019. View at Publisher · View at Google Scholar