Omega-9 Oleic Acid, the Main Compound of Olive Oil, Mitigates Inflammation during Experimental Sepsis

Figure 4

Omega-9 reduced rolling flux fraction in cremaster in trauma and TNF models. We treated the animals with omega-9 for 8 days prior to the experiments. On the day 9, we analyzed rolling in postcapillary venules of mouse cremaster muscle in two models: trauma (a) and TNF (b) models. We also treated animals of the trauma model with anti-P-selectin and of the TNF model with anti-P- and E-selectins. Rolling flux fraction was analyzed. Each bar is mean from at least 5 animals. and + compared to sham and sham + omega-9, respectively, and # compared to CLP.

(a)

(b)