Review Article

Emerging Role of mTOR Signaling-Related miRNAs in Cardiovascular Diseases

Figure 2

Illustration of miRNA biogenesis pathway and mode of gene regulation. RNA polymerase (RNA-Pol); Drosha; DiGeorge syndrome critical region-8 (DGCR8); guanosine triphosphate (GTP); RAs-related nuclear protein (Ran); human immunodeficiency virus trans-activating response RNA-binding protein (TRBP); argonaute 2 (Ago2); RNA-induced silencing complex (RISC); protein kinase RNA activator (PACT); open reading frame (ORF); 3′ untranslated region (3′UTR).