Isopropyl Caffeate: A Caffeic Acid Derivative—Antioxidant Potential and Toxicity

Figure 15

Liver of treated Balb/c females V.O., stained with hematoxylin and eosin (increase 200x), there was no sign of toxicity in the liver. The arrows appoint portal spaces and the asterisks appoint normal hepatocytes. (a) Control group vehicle. (b) Group treated with a dose of 300 mg/kg. (c) Group treated with a dose of 2000 mg/kg. (d) Animal treated with a dose of 2000 mg/kg with little inflammatory infiltrate portal (portal spaces (arrow) with mild chronic inflammatory infiltration). (e) Animal treated with a dose of 2000 mg/kg (portal spaces (arrow) with moderate chronic inflammatory infiltration).

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