Review Article
Nanoparticles in Medicine: A Focus on Vascular Oxidative Stress
Figure 2
The Nox 4 paradox. Vascular Nox 4 generates superoxide anion (O2ā) and hydrogen peroxide (H2O2). Depending on which via predominates, Nox 4 activation can be damaging or protective. VSCMs: vascular smooth muscle cells.