Dietary DHA/EPA Ratio Changes Fatty Acid Composition and Attenuates Diet-Induced Accumulation of Lipid in the Liver of ApoE^−/− Mice

Figure 1

Effects of the supplementation of various DHA/EPA ratios on hepatic lipid metabolism. H&E staining of liver sections in each group, followed by observation under a light microscope (magnification 200x). Notice the fatty vesicles (black arrow) and lymphocyte infiltration (red arrow). (a) Normal diet (ND) group, (b) high-fat diet (HFD) group, (c) DHA/EPA 2 : 1 (DHA/EPA = 2 : 1) group, (d) DHA/EPA 1 : 1 (DHA/EPA = 1 : 1) group, and (e) DHA/EPA 1 : 2 (DHA/EPA = 1 : 2) group.

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