Hydrogen Sulfide Biochemistry and Interplay with Other Gaseous Mediators in Mammalian Physiology

Figure 9

Crystallographic structure of human persulfide dioxygenase (ETHE1). (a) Cartoon representation of human ETHE1 homodimer (PDB ID: 4CHL; 2.61 Å resolution). (b) Zoom-in into the mononuclear nonheme iron catalytic site. Iron ligands (His₇₉, His₁₃₅, and Asp₁₅₄; human ETHE1 numbering) are represented in sticks. Figure generated with PyMol 1.8.2.0 [238].