Research Article
The Role of TLR4 on PGC-1α-Mediated Oxidative Stress in Tubular Cell in Diabetic Kidney Disease
Table 2
Physical and metabolic parameters in mice.
| | db/m | db/db | db/db + TAK242 |
| Body weight (g) | 35.9 ± 0.52 | 64.00 ± 5.02 | 58.42 ± 1.54 | Blood urea nitrogen (mmol/L) | 5.59 ± 0.36 | 11.42 ± 0.88 | 7.04 ± 0.38 | Serum creatinine (μmol/L) | 3.76 ± 0.19 | 16.77 ± 0.92 | 8.91 ± 0.35 | Urine protein (mg/24 h) | 7.53 ± 0.35 | 26.30 ± 1.15 | 15.31 ± 0.66 | ACR (μg/mg Cr) | 0.23 ± 0.01 | 2.89 ± 0.07 | 2.76 ± 0.08 |
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Values are ; , compared with the db/m group; , compared with the db/db group; urinary albumin : creatinine ratio (ACR). |