Transduced PEP-1-Heme Oxygenase-1 Fusion Protein Attenuates Lung Injury in Septic Shock Rats

Table 2

Changes in heart rate at specific time points for each group (beats/min, ).

Group	0 h	4 h	8 h	12 h
Sham	327.13 ± 4.38	328.00 ± 4.02	324.13 ± 4.31	325.25 ± 3.30
CLP	326.88 ± 3.82	369.50 ± 5.10	388.25 ± 3.09	395.38 ± 4.28
LD	324.63 ± 4.15	352.88 ± 3.92^,#	367.50 ± 3.22^,#	376.75 ± 3.74^,#
HD	331.75 ± 3.43	348.88 ± 2.89^,#	362.75 ± 3.72^,#	369.50 ± 3.17^,#

Values are expressed as mean ± SEM. versus the sham group; versus the CLP group. CLP: cecal ligation and puncture; LD: CLP + low-dose PEP-1-HO-1 fusion protein; HD: CLP + high-dose PEP-1-HO-1 fusion protein.