Protective Role of UCP2 in Oxidative Stress and Apoptosis during the Silent Phase of an Experimental Model of Epilepsy Induced by Pilocarpine

<div>Phospho-AKT expression in the hippocampus CA1, CA3, and dentate gyrus regions of the acute (5 hours after SE (5H)), silent (5 days after SE (5D)), and chronic (60 days after SE (60D)) groups. (a) Rat hippocampal formation with Nissl staining highlighting the CA1, CA3, and dentate gyrus areas. (b) Photomicrographs of the CA1, CA3, and dentate gyrus regions of the rat hippocampus after SE processed for phospho-AKT (p-AKT) immunohistochemistry and respective controls. Pilocarpine-treated animals at the 5th day after SE (silent phase) showed higher expression of p-AKT in comparison to any other group. ×100 augmentation (10x objective).</div>

Oxidative Medicine and Cellular Longevity

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Figure 3

Figure 3: Protective Role of UCP2 in Oxidative Stress and Apoptosis during the Silent Phase of an Experimental Model of Epilepsy Induced by Pilocarpine 

Figure 3 | Protective Role of UCP2 in Oxidative Stress and Apoptosis during the Silent Phase of an Experimental Model of Epilepsy Induced by Pilocarpine 