Redox Balance, Antioxidant Defense, and Oxidative Damage in the Hypothalamus and Cerebral Cortex of Rats with High Fat Diet-Induced Insulin Resistance

<div>Oxidative damage to the cerebral cortex and hypothalamus of the control and HFD-fed rats. 4-HNE, 4-hydroxynonenal protein adducts; 8-OHdG, 8-hydroxy-2<svg height="11.4859pt" id="M40" style="vertical-align:-0.04979992pt" version="1.1" viewbox="-0.0498162 -11.4361 3.89517 11.4859" width="3.89517pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M310 541L304 571C290 586 211 619 185 610L80 76L131 52L310 541Z" id="g50-31"></path></g></svg>-deoxyguanosine; AGE, advanced glycation end products; HFD, high fat diet; MDA, malondialdehyde. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Redox Balance, Antioxidant Defense, and Oxidative Damage in the Hypothalamus and Cerebral Cortex of Rats with High Fat Diet-Induced Insulin Resistance 

Figure 4 | Redox Balance, Antioxidant Defense, and Oxidative Damage in the Hypothalamus and Cerebral Cortex of Rats with High Fat Diet-Induced Insulin Resistance 