Research Article

Effect of Metronidazole on the Oxidoreductive Processes in the Submandibular and Parotid Glands in Experimental Research

Table 1

Evaluation of enzymatic and nonenzymatic parameters in the rat salivary glands.

ParametersSubmandibular glandParotid gland
Control (C)Metronidazole (MTZ)Control (C)Metronidazole (MTZ)

GPx (mU/mg protein)28.120 ± 0.67721.910 ± 0.94215.820 ± 0.722†††13.680 ± 0.595†††
CAT (mU/mg protein)11.190 ± 0.4417.478 ± 0.48016.100 ± 0.505†††9.436 ± 0.490††
SOD (U/mg protein)0.423 ± 0.0190.309 ± 0.0420.438 ± 0.0250.279 ± 0.016
GSH (nmol/mg protein)0.356 ± 0.0160.363 ± 0.0100.406 ± 0.0280.366 ± 0.016
LPO (nmol/mg protein)0.393 ± 0.0250.493 ± 0.0250.341 ± 0.0150.516 ± 0.063
TAS (nmol/mg protein)13.190 ± 0.8604.779 ± 0.42312.860 ± 1.0873.668 ± 0.303
TOS (nmol/mg protein)57.650 ± 2.01985.890 ± 3.82230.990 ± 2.419†††63.730 ± 2.748
TOS/TAS4.446 ± 0.19418.590 ± 1.0922.487 ± 0.19618.250 ± 1.645

Relative to the control group, , . Relative to the submandibular gland, .