Toxic Effects of Trazodone on Male Reproductive System via Disrupting Hypothalamic-Pituitary-Testicular Axis and Inducing Testicular Oxidative Stress

Table 5

Effects of TRZ on MDA and GSH levels in testis tissues of male rats.

	C	TRZ-5	TRZ-10	TRZ-20
MDA (pmol ml^−)	424.03 ± 10.69	543.78 ± 8.09	590.58 ± 8.31	690.83 ± 11.08
GSH (μM)	24.55 ± 1.86	25.18 ± 0.96	24.70 ± 1.24	25.20 ± 1.21

C: control group; TRZ-5: 5 mg kg⁻¹ trazodone-treated rats for the 28-day group; TRZ-10: 10 mg kg⁻¹ trazodone-treated rats for the 28-day group; TRZ-20: 20 mg kg⁻¹ trazodone-treated rats for the 28-day group. All data were expressed as mean ± standard error. Different from C ().