Quercetin Prevents Diastolic Dysfunction Induced by a High-Cholesterol Diet: Role of Oxidative Stress and Bioenergetics in Hyperglycemic Rats

Figure 8

Quercetin protects against the decrease in ATP levels and the alterations of metabolic gene expression induced by high-cholesterol diet. (a) ATP levels, (b) PGC-1α, and (c) UCP2 expression in the hearts of rats fed for 4 weeks with control diet (C), control diet containing 0.5% quercetin diet (CQ), high-cholesterol diet (HC), and high-cholesterol diet containing 0.5% quercetin (HCQ). Values are expressed as mean ± SEM. rats/group. Two-way ANOVA test and Bonferroni posttest. Statistical differences: and .

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