Protocatechuic Acid Attenuates Trabecular Bone Loss in Ovariectomized Mice

Figure 9

Summary of inhibitory potential of PCA against osteoclastogenesis in OVX mice. NFATc1: nuclear factor of activated T cell cytoplasmic 1; OPG: osteoprotegerin; PCA: protocatechuic acid; RANK: receptor activator of nuclear factor κB; RANKL: RANK ligand; TRAF6: TNF receptor-associated factor-6; (+): increase; (-): decrease.