Research Article
Impact of Ileal Transposition Surgical Intervention on Antioxidant Status Measured in Liver Tissue of Obese Zucker Rats (Crl:ZUC-Leprfa)
Table 1
Antioxidant concentration and activity in liver tissue 3 months after IT surgery. Statistical significance was set at
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| | Control | Sham | IT | p | p 1 Control vs sham | p 2 IT vs control | p 3 IT vs sham |
| TAC (μmol/g) | 148.71 ± 15.71 | 115.63 ± 6.68 | 175.62 ± 17.29 | <0.001 | <0.01 | <0.01 | <0.001 | TOS (μmol/g) | 0.27 ± 0.07 | 0.15 ± 0.03 | 0.26 ± 0.05 | <0.001 | <0.01 | 0.939 | <0.01 | GPx (IU/g) | 72.02 ± 15.77 | 190.70 ± 31.32 | 161.21 ± 35.24 | <0.001 | <0.001 | <0.001 | 0.177 | GR (IU/g) | 64.09 ± 27.74 | 34.22 ± 11.40 | 89.36 ± 19.50 | <0.001 | <0.01 | <0.05 | <0.001 | CAT (IU/g) | 338.38 ± 68.20 | 333.22 ± 42.85 | 676.43 ± 160.44 | <0.001 | 0.996 | <0.001 | <0.001 | Total SOD (NU/mg) | 477.12 ± 44.51 | 579.82 ± 69.38 | 478.24 ± 96.53 | <0.05 | <0.05 | 0.999 | <0.05 | MnSOD (NU/mg) | 91.09 ± 20.43 | 126.10 ± 38.10 | 65.49 ± 11.60 | <0.001 | <0.05 | 0.145 | <0.001 | GST (IU/g) | 35.29 ± 1.63 | 40.31 ± 4.84 | 38.16 ± 6.46 | 0.179 | — | — | — | CuZnSOD (NU/mg) | 386.27 ± 47.40 | 439.41 ± 60.06 | 368.75 ± 71.10 | 0.086 | — | — | — |
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Abbreviations: GPX: glutathione peroxidase; GR: glutathione reductase; CAT: catalase, SOD: total superoxide dismutase; MnSOD: Mn superoxide dismutase; ZnSOD: Zn superoxide dismutase; GST: glutathione S-transferase: TAC: total antioxidant capacity; TOS: total oxidative status.
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