Research Article

Impact of Ileal Transposition Surgical Intervention on Antioxidant Status Measured in Liver Tissue of Obese Zucker Rats (Crl:ZUC-Leprfa)

Table 1

Antioxidant concentration and activity in liver tissue 3 months after IT surgery. Statistical significance was set at .

ControlShamITpp 1
Control vs sham
p 2
IT vs control
p 3
IT vs sham

TAC (μmol/g)148.71 ± 15.71115.63 ± 6.68175.62 ± 17.29<0.001<0.01<0.01<0.001
TOS (μmol/g)0.27 ± 0.070.15 ± 0.030.26 ± 0.05<0.001<0.010.939<0.01
GPx (IU/g)72.02 ± 15.77190.70 ± 31.32161.21 ± 35.24<0.001<0.001<0.0010.177
GR (IU/g)64.09 ± 27.7434.22 ± 11.4089.36 ± 19.50<0.001<0.01<0.05<0.001
CAT (IU/g)338.38 ± 68.20333.22 ± 42.85676.43 ± 160.44<0.0010.996<0.001<0.001
Total SOD (NU/mg)477.12 ± 44.51579.82 ± 69.38478.24 ± 96.53<0.05<0.050.999<0.05
MnSOD (NU/mg)91.09 ± 20.43126.10 ± 38.1065.49 ± 11.60<0.001<0.050.145<0.001
GST (IU/g)35.29 ± 1.6340.31 ± 4.8438.16 ± 6.460.179
CuZnSOD (NU/mg)386.27 ± 47.40439.41 ± 60.06368.75 ± 71.100.086

Abbreviations: GPX: glutathione peroxidase; GR: glutathione reductase; CAT: catalase, SOD: total superoxide dismutase; MnSOD: Mn superoxide dismutase; ZnSOD: Zn superoxide dismutase; GST: glutathione S-transferase: TAC: total antioxidant capacity; TOS: total oxidative status.