Decreased Oxidative Stress in Male Patients with Active Phase Ankylosing Spondylitis Who Underwent Whole-Body Cryotherapy in Closed Cryochamber
Table 2
Activities of antioxidant enzymes (mean value ± standard deviation SD) in AS patients before and after the completion of a cycle of ten whole-body cryotherapy procedures with subsequent kinesiotherapy (WBC group) or a cycle of ten kinesiotherapy procedures only (KT group), with statistical analyses. (p): plasma; (e): erythrocyte lysates; Δ: difference prior to post treatment.
Parameters
WBC group
KT group
Total SOD (p) [NU/ml]
Before
12.4 ± 1.89
12.3 ± 1.85
0.927
After
11.5 ± 3.19
11.7 ± 2.49
0.884
0.501
0.301
Δ
−0.81 ± 3.08
−0.60 ± 2.65
0.837
SOD-Mn (p) [NU/ml]
Before
5.31 ± 1.03
4.56 ± 1.86
0.170
After
6.32 ± 2.16
5.02 ± 1.64
0.066
0.098
0.642
Δ
1.01 ± 2.15
0.46 ± 2.46
0.509
SOD-CuZn (p) [NU/ml]
Before
7.05 ± 1.92
7.80 ± 2.21
0.310
After
5.76 ± 2.36
7.05 ± 3.09
0.194
0.063
0.326
Δ
−1.29 ± 2.46
−0.75 ± 2.72
0.166
Total SOD (e) [NU/mgHb]
Before
104.0 ± 15.0
128.0 ± 11.2
<0.001
After
112.0 ± 11.2
111.0 ± 15.6
0.759
0.056
0.001
Δ
7.77 ± 17.2
−17.1 ± 11.8
<0.001
CAT (e) [IU/mgHb]
Before
423.0 ± 61.6
425.0 ± 53.6
0.914
After
380.0 ± 102.0
412.0 ± 58.6
0.294
0.079
0.352
Δ
−42.3 ± 109.0
−13.0 ± 54.0
0.347
GPx (e) [IU/gHb]
Before
20.6 ± 5.07
29.9 ± 2.84
<0.001
After
18.3 ± 4.15
20.4 ± 5.05
0.207
0.002
0.001
Δ
−2.27 ± 1.98
−9.49 ± 6.74
0.001
GR (e) [IU/gHb]
Before
1.21 ± 0.29
2.07 ± 0.52
<0.001
After
0.93 ± 0.37
1.65 ± 0.59
<0.001
0.007
0.002
Δ
−0.28 ± 0.34
−0.42 ± 0.41
0.275
: statistical significance of differences between both groups of patients; : statistical significance of differences between values before and after treatment in particular groups of subjects.