Research Article

Decreased Oxidative Stress in Male Patients with Active Phase Ankylosing Spondylitis Who Underwent Whole-Body Cryotherapy in Closed Cryochamber

Table 2

Activities of antioxidant enzymes (mean value ± standard deviation SD) in AS patients before and after the completion of a cycle of ten whole-body cryotherapy procedures with subsequent kinesiotherapy (WBC group) or a cycle of ten kinesiotherapy procedures only (KT group), with statistical analyses. (p): plasma; (e): erythrocyte lysates; Δ: difference prior to post treatment.

ParametersWBC groupKT group

Total SOD (p)
[NU/ml]
Before12.4 ± 1.8912.3 ± 1.850.927
After11.5 ± 3.1911.7 ± 2.490.884
0.5010.301
Δ−0.81 ± 3.08−0.60 ± 2.650.837

SOD-Mn (p)
[NU/ml]
Before5.31 ± 1.034.56 ± 1.860.170
After6.32 ± 2.165.02 ± 1.640.066
0.0980.642
Δ1.01 ± 2.150.46 ± 2.460.509

SOD-CuZn (p)
[NU/ml]
Before7.05 ± 1.927.80 ± 2.210.310
After5.76 ± 2.367.05 ± 3.090.194
0.0630.326
Δ−1.29 ± 2.46−0.75 ± 2.720.166

Total SOD (e)
[NU/mgHb]
Before104.0 ± 15.0128.0 ± 11.2<0.001
After112.0 ± 11.2111.0 ± 15.60.759
0.0560.001
Δ7.77 ± 17.2−17.1 ± 11.8<0.001

CAT (e)
[IU/mgHb]
Before423.0 ± 61.6425.0 ± 53.60.914
After380.0 ± 102.0412.0 ± 58.60.294
0.0790.352
Δ−42.3 ± 109.0−13.0 ± 54.00.347

GPx (e)
[IU/gHb]
Before20.6 ± 5.0729.9 ± 2.84<0.001
After18.3 ± 4.1520.4 ± 5.050.207
0.0020.001
Δ−2.27 ± 1.98−9.49 ± 6.740.001

GR (e)
[IU/gHb]
Before1.21 ± 0.292.07 ± 0.52<0.001
After0.93 ± 0.371.65 ± 0.59<0.001
0.0070.002
Δ−0.28 ± 0.34−0.42 ± 0.410.275

: statistical significance of differences between both groups of patients; : statistical significance of differences between values before and after treatment in particular groups of subjects.