The Antidiabetic and Antinephritic Activities of <i>Tuber melanosporum</i> via Modulation of Nrf2-Mediated Oxidative Stress in the db/db Mouse

<div>Eight-week TM treatment affected the levels of the (a) NAG, (b) 6-keto-PGF1<i>α</i>, (c) MCP-5, and (d) MMP-9 in the kidney of db/db mice. 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Histopathological analysis in kidney was shown by (e) H&amp;E staining (scale bar: 20 <i>μ</i>m; magnification: 400x) and (f) PAS staining (scale bar: 20 <i>μ</i>m; magnification: 400x). TM: <i>T. melanosporum</i>; NAG: n-acetyl-<i>β</i>-d-glucosaminidase; 6-keto-PGF1<i>α</i>: 6-keto prostaglandin F1<i>α</i>; MCP-5: monocyte chemotactic protein-5; MMP-9: matrix metalloproteinase-9; H&amp;E: Hematoxylin and eosin; PAS: periodic acid Schiff.</div>

Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: The Antidiabetic and Antinephritic Activities of <i>Tuber melanosporum</i> via Modulation of Nrf2-Mediated Oxidative Stress in the db/db Mouse 

Oxidative Medicine and Cellular Longevity

The Antidiabetic and Antinephritic Activities of Tuber melanosporum via Modulation of Nrf2-Mediated Oxidative Stress in the db/db Mouse

Figure 3