Oxygen Concentration and Oxidative Stress Modulate the Influence of Alzheimer’s Disease Aβ_1–42 Peptide on Human Cells

Figure 1

FITC-labelled Aβ_1–42 peptide interacts with SH-SY5Y cells. Flow cytometry analysis: shift in the fluorescence signal in SH-SY5Y cells cultivated at 21% O₂ incubated with FITC-Aβ_1–42 peptide after 15 min, 1, 3, 18, and 24 h compared to unstained cells. Maximum fluorescence signal occurred after 18 h, whereas a slight decrease of the signal was detected after 24 h.

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