Research Article
Oxygen Concentration and Oxidative Stress Modulate the Influence of Alzheimer’s Disease Aβ1–42 Peptide on Human Cells
Figure 2
FITC-labelled Aβ1–42 peptide interacts with lysosomes of SH-SY5Y cells. FITC-Aβ1–42 peptide (green fluorescence) interacts with acidic organelles (lysosomes; late endosomes as dotted structures in selected regions (white squares) of overlay images enlarged on the right side of the panel) stained by LysoTracker Red dye (red fluorescence) at both 21% and 5% O2; progressive interaction after 3, 8, and 18 h. 400x magnification. 50 μm scale bar.
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