Research Article

Oxygen Concentration and Oxidative Stress Modulate the Influence of Alzheimer’s Disease Aβ1–42 Peptide on Human Cells

Figure 3

Interaction of FITC-Aβ peptide with the mitochondria and endoplasmatic reticulum. Weak colocalization of FITC-Aβ peptide with the mitochondria stained by MitoTracker Red (red fluorescence) (a) and with endoplasmatic reticulum stained by ER-Tracker Red dye (red fluorescence) (b) at both 21% and 5% O2, documented after 18 h. Selected regions (white squares) of overlay images enlarged on the right side of the panel for better visualization. 400x magnification. 50 μm scale bar.
(a)
(b)