Analysis of Plasma MicroRNAs as Predictors and Biomarkers of Aging and Frailty in Humans

Table 1

Characteristics of the studied subjects.

Item	Control group	Aged without frailty	Aged with frailty
Number of subjects	22	34	40
Age	20.5 ± 2.4	76.6 ± 5.3	84.4 ± 5.6
Gender (male/female)
Male	19 (86%)	12 (35%)	13 (33%)
Female	3 (14%)	22 (65%)	27 (67%)
<80 years old (M/F)	0	24 (10/14)	8 (2/6)
≥80 years old (M/F)	0	10 (2/8)	32 (11/21)
Physical activity	n.m.	79.69 ± 8.05	10.77 ± 2.76^###
Physical dependence	0%	12%	75%^###
Hypertension	0%	38%	32%

Age and physical activity are expressed as the means ± SEM. M/F: male/female; n.m.: not measured. versus the control group; versus aged without frailty.