Andrographolide Ameliorates Liver Fibrosis in Mice: Involvement of TLR4/NF-κB and TGF-β1/Smad2 Signaling Pathways

Figure 3

Andro reduced inflammation in CCl₄-induced mice through inhibition of the TLR4/NF-κB signaling pathway. (a) Representative immunohistochemical staining of TLR4. (b) Representative immunofluorescent staining of NF-κB p-p50. (c, d) Quantification of positive staining areas was measured by ImageJ software. (e) The protein expression of TLR4 was examined by Western blot. . versus control mice. versus mice induced by CCl₄.

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