Clinical Study

Urinary Mitochondrial DNA Identifies Renal Dysfunction and Mitochondrial Damage in Sepsis-Induced Acute Kidney Injury

Figure 6

Urinary mitochondrial DNA (UmtDNA) is a biomarker of renal dysfunction following cecal ligation and puncture- (CLP) induced AKI in rats. Receiver operating characteristic curves were constructed for UmtDNA comparing (a) the sham group to rats that underwent CLP or (b) no AKI rats to AKI rat following sepsis. AKI: acute kidney injury.