Urinary Mitochondrial DNA Identifies Renal Dysfunction and Mitochondrial Damage in Sepsis-Induced Acute Kidney Injury

Table 2

Correlations between plasma mtDNA and markers of systemic inflammation and kidney injury in sepsis patients.

	Plasma COX3 levels	Plasma ND1 levels
Inflammation
Leukocyte count	;	;
Plasma CRP	;	;
Plasma PCT	;	;
Plasma IL-6 (pg/mL)	;	;
Renal Function
Plasma creatinine (μmol/L)	;	;
Urinary NGAL	;	;
Urinary KIM-1	;	;

Linear regression was performed and Spearman’s rank-order coefficients were calculated. CRP: C-reactive protein; PCT: procalcitonin; NGAL: neutrophil gelatinase-associated lipocalin; KIM-1: kidney injury molecule-1. indicates significant correlations.