Black Seed Thymoquinone Improved Insulin Secretion, Hepatic Glycogen Storage, and Oxidative Stress in Streptozotocin-Induced Diabetic Male Wistar Rats

Figure 2

H&E stain of liver: (a) control group and (b) Nigella-treated rats demonstrate normal hepatic architecture showing the classic lobule with the central vein at the center and portal tracts at the periphery; each one is separated from the others by a similar distance, 100x. (c) Diabetic group showing ballooning degeneration of the hepatocyte (, 40x), and interface hepatitis (arrow), 100x. (d) NSO-treated diabetic group showing restoration of normal architecture, 100x. Scale bar represents 100 μm.

(a)

(b)

(c)

(d)