Review Article
How Supraphysiological Oxygen Levels in Standard Cell Culture Affect Oxygen-Consuming Reactions
Figure 1
Sites of H2O2 production in the mitochondrial electron transport chain. These include 2-oxoacid dehydrogenase, complex I (site IF), complex I (site IQ), complex II (site IIF), complex III (site IIIQ0), the ETFQOR system (site EF), glycerol 3-phosphate dehydrogenase (site Gq), and dihydroorotate dehydrogenase (site Dq). Complex I: O00217 (Homo sapiens); complex II: Q0QF01 (Sus scrofa); complex III: P23004 (Bos taurus); complex IV: P68530 (Bos taurus); ATP synthase O00217 (Bos taurus); cytochrome c: P99999 (Homo sapiens); glycerol 3-phosphate: P04406 (Homo sapiens); dihydroorotate dehydrogenase: ID3H (Homo sapiens); 2-oxoacid dehydrogenase: 2DNE (Homo sapiens); ETFQOR: 2GMH (Sus scrofa). Data based on Wong et al. [10]. Structures retrieved from https://www.rcsb.org/.