Role of Oxidative and Nitro-Oxidative Damage in Silver Nanoparticles Cytotoxic Effect against Human Pancreatic Ductal Adenocarcinoma Cells

Table 2

IC₅₀ values obtained after treatment of PANC-1 and hTERT-HPNE cells with 2.6 and 18 nm AgNPs.

	IC50 from LDH	IC50 from MTT	IC50 from LDH	IC50 from MTT
	(μg/mL)	(μg/mL)	(μg/mL)	(μg/mL)
PANC-1	3.19	1.67	56.46	26.81
hTERT-HPNE	8.06	3.74	160.3	58.46
	2.6 nm AgNPs		18 nm AgNPs

The inhibitory concentration, IC₅₀, was calculated from the following equation: log (inhibitor) versus responses curve using the GraphPad Prism 5 program.