Protective Effects of Taraxasterol against Ethanol-Induced Liver Injury by Regulating CYP2E1/Nrf2/HO-1 and NF-<i>κ</i>B Signaling Pathways in Mice

<div>Effects of taraxasterol on the production of ROS, the levels of MDA and GSH, and the activity of SOD in liver tissues of mice with ethanol-induced liver injury. The mice were treated with taraxasterol (2.5, 5, and 10 mg/kg, respectively) or TPN and induced with EtOH as described in Materials and Methods. The production of ROS, the levels of MDA and GSH, and the activity of SOD in liver tissues were determined by commercial reagent kits. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Protective Effects of Taraxasterol against Ethanol-Induced Liver Injury by Regulating CYP2E1/Nrf2/HO-1 and NF-<i>κ</i>B Signaling Pathways in Mice 

Figure 4 | Protective Effects of Taraxasterol against Ethanol-Induced Liver Injury by Regulating CYP2E1/Nrf2/HO-1 and NF-κB Signaling Pathways in Mice 