Oxidative Medicine and Cellular Longevity / 2018 / Article / Fig 4

Research Article

Protective Effects of Taraxasterol against Ethanol-Induced Liver Injury by Regulating CYP2E1/Nrf2/HO-1 and NF-κB Signaling Pathways in Mice

Figure 4

Effects of taraxasterol on the production of ROS, the levels of MDA and GSH, and the activity of SOD in liver tissues of mice with ethanol-induced liver injury. The mice were treated with taraxasterol (2.5, 5, and 10 mg/kg, respectively) or TPN and induced with EtOH as described in Materials and Methods. The production of ROS, the levels of MDA and GSH, and the activity of SOD in liver tissues were determined by commercial reagent kits. The values represent the means ± SEMs and are expressed as % of normal, nmol/mg of protein, μmol/g of protein, and U/mg of protein, respectively. vs. normal group; and vs. EtOH group.

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