The Associations between Infertility and Antioxidants, Proinflammatory Cytokines, and Chemokines

Table 5

Concentrations of cytokines in seminal plasma (IL-1β: interleukin 1β; IL-6: interleukin 6; IL-8: interleukin 8; IL-12 interleukin 12; MCP-1: monocyte chemoattractant protein-1; MIP-1β: macrophage inflammatory protein 1-β; TNF-α: tumor necrosis factor α; -value—Mann–Whitney test.

	Control		Oligospermia				Asthenospermia				Oligoasthenospermia
	Median	IQR	Median	IQR	relative change	value	Median	IQR	relative change	value	Median	IQR	relative change	value
IL-1β (pg/ml)	1.21	2.61	1.98	10.52	64%	0.164	1.66	9.90	37%	0.134	1.65	9.93	36%	0.198
IL-6 (pg/ml)	9.97	13.0	13.5	18.7	35%	0.161	15.90	16.4	59%	0.177	17.0	17.4	71%	0.064
IL-8 (pg/ml)	155	157	242	371	56%	0.092	254	437	64%	0.017	259	423	67%	0.038
IL-12 (pg/ml)	2.80	3.72	1.56	3.40	−44%	0.108	2.22	3.74	−21%	0.296	1.39	2.99	−50%	0.041
MCP-1 (pg/ml)	992	1181	1347	1411	36%	0.221	1457	1387	47%	0.038	1624	1467	64%	0.041
MIP-1β (pg/ml)	50.9	31.0	79.8	111	57%	0.006	74.9	76.7	47%	0.013	75.8	72.2	49%	0.016
TNF-α (pg/ml)	4.13	3.39	3.73	4.16	−10%	0.326	3.88	3.68	−6%	0.361	3.67	4.16	−11%	0.318

IQR: interquartile range, .