Combination of Coenzyme Q₁₀ Intake and Moderate Physical Activity Counteracts Mitochondrial Dysfunctions in a SAMP8 Mouse Model

Figure 5

(a) TEM analysis of mitochondrial ultrastructure of soleus muscle (SED, ; inset SED, ; PHY, ; QH₂, ; and QH₂ + PHY, inset, and QH₂ + PHY, ). (b) Mitochondrial membrane depolarization expressed as Red2 Fluorescent (RED2-HLog). (c) Percentage of depolarized cells of gastrocnemius muscle, respectively, in sedentary (black histogram; SED), physical exercise (light grey histogram; PHY), ubiquinol (dark grey histogram; QH₂), and ubiquinol associated with physical exercise (dark grey histogram; QH₂ + PHY) mouse groups (). Dashed histogram (b) represents sample control treated with CCCP and ; (A) = vs. SED and (B) = vs. PHY.

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