Research Article

Ascorbate Attenuates Oxidative Stress and Increased Blood Pressure Induced by 2-(4-Hydroxyphenyl) Amino-1,4-naphthoquinone in Rats

Table 1

Ascorbate decreases intracellular calcium levels in the presence of Q7 in vascular smooth muscle cells (A7r5). The A7r5 cells were preincubated with 10−5 M Q7 and/or 2 mM ascorbate (Asc) for 20 min.

ControlQ7Q7+AscAsc

Ca2+ signal (Fluo-3 fluorescence)209 ± 15296 ± 23230 ± 16201 ± 10

Values are mean ± standard error of the mean of 3 experiments. Statistically significant differences: versus control.