Flavocoxid, a Natural Antioxidant, Protects Mouse Kidney from Cadmium-Induced Toxicity

Table 1

Urea nitrogen and creatinine levels in mice exposed to cadmium chloride (CdCl₂; 2 mg/kg i.p.) plus vehicle, as compared to mice exposed to CdCl₂ (2 mg/kg i.p.) plus flavocoxid (20 mg/kg/day i.p.) or to control mice treated with vehicle or flavocoxid alone.

	Urea nitrogen (mg/dl)	Creatinine (mg/dl)
Control + vehicle	13.6 ± 1.3	0.58 ± 0.04
Control + flavocoxid	13.9 ± 1.4	0.61 ± 0.08
CdCl2 + vehicle	39.3 ± 4.4^a	1.48 ± 0.18^a
CdCl2 + flavocoxid	17.5 ± 2.2^b	0.71 ± 0.09^b

All the values are expressed as , animals for each group. versus both controls and versus CdCl₂ + vehicle.