Flavocoxid, a Natural Antioxidant, Protects Mouse Kidney from Cadmium-Induced Toxicity

Table 3

Glutathione reductase (GR) and glutathione peroxidase (GPx) levels in mice exposed to cadmium chloride (CdCl₂; 2 mg/kg i.p.) plus vehicle, as compared to mice exposed to CdCl₂ (2 mg/kg i.p.) plus flavocoxid (20 mg/kg/day i.p.) or to control mice treated with vehicle or flavocoxid alone.

	GR (nmol/min per mg protein)	GPx (nmol/min per mg protein)
Control + vehicle	20.03 ± 1.12	33.42 ± 1.78
Control + flavocoxid	19.83 ± 1.04	31.64 ± 1.83
CdCl2 + vehicle	12.64 ± 0.63^a	18.72 ± 0.87^a
CdCl2 + flavocoxid	18.35 ± 1.01^b	28.69 ± 1.53^b

All the values are expressed as , animals for each group. versus both controls and versus CdCl₂ + vehicle.